Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_CANONICAL NF-KAPPAB PATHWAY |
| Enrichment Score (ES) | -0.67032593 |
| Normalized Enrichment Score (NES) | -1.5242597 |
| Nominal p-value | 0.016990291 |
| FDR q-value | 0.3669127 |
| FWER p-Value | 0.995 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | ARRB2 | 2060441 | 811 | 3.434 | 0.0219 | No | ||
| 2 | NFKB1 | 5420358 | 1663 | 2.059 | 0.0154 | No | ||
| 3 | BCL3 | 3990440 | 3080 | 0.830 | -0.0449 | No | ||
| 4 | PRKCA | 6400551 | 3491 | 0.607 | -0.0554 | No | ||
| 5 | PIK3R1 | 4730671 | 7309 | 0.074 | -0.2594 | No | ||
| 6 | REL | 360707 | 8670 | 0.039 | -0.3319 | No | ||
| 7 | RAN | 2260446 4590647 | 9366 | 0.026 | -0.3688 | No | ||
| 8 | XPO1 | 540707 | 9448 | 0.024 | -0.3727 | No | ||
| 9 | ATM | 3610110 4050524 | 10891 | 0.001 | -0.4503 | No | ||
| 10 | TNF | 6650603 | 12392 | -0.029 | -0.5304 | No | ||
| 11 | FBXW11 | 6450632 | 13105 | -0.052 | -0.5677 | No | ||
| 12 | SRC | 580132 | 13241 | -0.057 | -0.5739 | No | ||
| 13 | SYK | 6940133 | 13698 | -0.084 | -0.5969 | No | ||
| 14 | PIK3CA | 6220129 | 13874 | -0.096 | -0.6044 | No | ||
| 15 | ERC1 | 1580170 2630717 6110762 6840280 | 14419 | -0.163 | -0.6306 | No | ||
| 16 | NOD2 | 2510050 | 14932 | -0.293 | -0.6526 | No | ||
| 17 | MALT1 | 4670292 | 14981 | -0.308 | -0.6493 | No | ||
| 18 | RELB | 1400048 | 15239 | -0.399 | -0.6555 | No | ||
| 19 | IKBKG | 3450092 3840377 6590592 | 15489 | -0.523 | -0.6589 | Yes | ||
| 20 | BIRC2 | 2940435 4730020 | 15520 | -0.538 | -0.6502 | Yes | ||
| 21 | UBE2D3 | 3190452 | 15655 | -0.609 | -0.6458 | Yes | ||
| 22 | NFKB2 | 2320670 | 15676 | -0.622 | -0.6350 | Yes | ||
| 23 | CYLD | 6590079 | 16333 | -1.029 | -0.6507 | Yes | ||
| 24 | RIPK2 | 5050072 6290632 | 16369 | -1.063 | -0.6323 | Yes | ||
| 25 | IKBKB | 6840072 | 16924 | -1.659 | -0.6304 | Yes | ||
| 26 | LCK | 3360142 | 17003 | -1.730 | -0.6016 | Yes | ||
| 27 | CHUK | 7050736 | 17108 | -1.856 | -0.5717 | Yes | ||
| 28 | TRAF6 | 4810292 6200132 | 17205 | -1.966 | -0.5394 | Yes | ||
| 29 | RELA | 3830075 | 17212 | -1.973 | -0.5020 | Yes | ||
| 30 | MAPK14 | 5290731 | 17669 | -2.766 | -0.4738 | Yes | ||
| 31 | NFKBIA | 1570152 | 17856 | -3.162 | -0.4234 | Yes | ||
| 32 | BCL10 | 2360397 | 18081 | -3.744 | -0.3640 | Yes | ||
| 33 | MAP3K14 | 5890435 | 18190 | -4.158 | -0.2904 | Yes | ||
| 34 | TNFAIP3 | 2900142 | 18558 | -7.288 | -0.1710 | Yes | ||
| 35 | TNFRSF1A | 1090390 6520735 | 18612 | -9.119 | 0.0002 | Yes |
